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Hypothyroidism

March 2007

• Hypothyroidism is more frequent after thyroid inflammation induced by amiodarone than after painful subacute thyroiditis
  
  
• The antitumor drug sunitinib can cause hypothyroidism
  
  
• Growth hormone therapy can cause central hypothyroidism in patients with hypopituitarism
  
  
• Hypertension and low serum potassium caused by excess salt-retaining hormone activity in hypothyroidism
  
  
• Serum insulin-like growth factor I increases in response to thyroxine in patients with hypothyroidism
  
  
• The effect of thyroxine is greater when taken at bedtime than in the morning in patients with hypothyroidism
  
  

November 2006

• Patients with subclinical hypothyroidism may have an increased risk of coronary heart disease
  
  
• Hypothyroidism in patients with adrenal insufficiency may disappear with adrenal hormone therapy
  
  
• Small changes in thyroxine dose do not alter symptoms or well-being in patients with hypothyroidism
  
  
• Therapy with thyroxine and triiodothyronine is not more effective than thyroxine alone in patients with hypothyroidism
  
  
• Administration of thyroxine into the amniotic fluid is effective therapy for goiter and hypothyroidism in fetuses

March 2006

• Subclinical hypothyroidism is not associated with neuropsychologic abnormalities or symptoms of hypothyroidism
  
  
• Fibrous tumors can cause consumptive hypothyroidism
  
  
• Patients with brain tumors treated with radiation may have hypopituitarism later

November 2005

• Hypothyroidism is common in older women treated with lithium
  
  
• Subclinical hypothyroidism may spontaneously remit months or years after diagnosis
  
  
• Initiation of therapy with a full dose of thyroxine in patients with hypothyroidism is safe, but not effective sooner than a low dose
  
  
• Patients with hypothyroidism who are treated with the antitumor drug imatinib need more thyroxine

July 2005

• Subclinical hypothyroidism rarely becomes more severe with time in women with type 2 diabetes
  
  
• Surgical removal of one thyroid lobe may result in hypothyroidism
  
  
• The symptoms and results of treatment of craniopharyngioma are similar in children and adults
  
  
• Combined thyroxine and triiodothyronine therapy is not more effective than thyroxine alone in patients with hypothyroidism (I)
  
  
• Combined thyroxine and triiodothyronine therapy is not more effective than thyroxine alone in patients with hypothyroidism (II)
  
  
• Combined thyroxine and triiodothyronine therapy is not more effective than thyroxine alone in patients with hypothyroidism (III)

March 2005

• Hypothyroidism rarely contributes to the need for prolonged mechanical ventilation in patients with lung disease

November 2004

• Subclinical hypothyroidism may disappear or progress to overt hypothyroidism
  
  
• Thyrotropin and other pituitary hormone deficiencies may occur after head trauma or bleeding
  
  
• Pregnancy increases the requirement for thyroxine in women with hypothyroidism

July 2004

• The thickness of the carotid arteries is increased in subclinical hypothyroidism
  
  
• Severe mental impairment and poor physiologic status predict mortality in patients with myxedema coma

• Thyroxine plus triiodothyronine and thyroxine alone have similar effects in patients with hypothyroidism
  
  
• Serum triiodothyronine concentrations change less after sustained-release triiodothyronine than standard triiodothyronine

March 2004

• Thyroxine plus triiodothyronine and thyroxine alone have similar efficacy in hypothyroid patients who have depressive symptoms

• Thyroxine plus triiodothyronine and thyroxine alone have similar efficacy in patients with hypothyroidism

• Thyroxine alone is as effective as triiodothyronine plus thyroxine in improving symptoms and cognitive function in hypothyroid patients

November 2003

1. Hypothyroidism may be increased in patients with human immunodeficiency virus infection

2. The success rate of in vitro fertilization of oocytes is reduced in women with high serum thyrotropin values

July 2003

• Serum C-reactive protein and homocysteine concentrations are increased in women with hypothyroidism

• Thyroxine therapy increases the pregnancy rate in women with mild thyroid hypofunction

March 2003

• Children with brain tumors may have hypothyroidism and other endocrine problems after treatment

• Hyperprolactinemia is rare and of minor clinical importance in patients with hypothyroidism

• Adequately treated patients with hypothyroidism feel less well than other patients

• Higher mortality after coronary-artery surgery in women treated with thyroxine than other women

November 2002

• Some patients with subclinical hypothyroidism have mutations in the gene for the thyrotropin receptor

• The severity of hypothyroidism is most likely to increase in patients with high serum thyrotropin values

• Patients with hypothyroidism may have high serum concentrations of several enzymes

• Thyroxine inhibits thyrotropin secretion in patients with pituitary disease

July 2002

• Thyroxine alone may reverse hypertension in some patients with hypothyroidism

• Lack of benefit of thyroxine in patients with mild subclinical hypothyroidism

• Hypothyroidism caused by thalidomide in patients with multiple myeloma

• Risk of hip fracture is not increased in women treated with thyroxine

• Hypothyroid patients with severe kidney disease need less thyroxine after renal transplantation

March 2002

• Thyroxine therapy does not improve well-being or cognitive function in patients with symptoms of hypothyroidism but normal thyroid function

• Radiation therapy can cause hypothyroidism in patients with head and neck cancer

• Central hypothyroidism is common in patients with hypopituitarism